AKAP5 Antikörper (AA 115-143)

Produktnummer ABIN1537769

Der Kaninchen Polyklonal anti-AKAP5 Antikörper wird verwendet zum Nachweis von AKAP5 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für AKAP5 Antikörper (AA 115-143) (ABIN1537769)

Target: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKAP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB39500

Produktdetails anti-AKAP5 Antikörper

Bindungsspezifität: AA 115-143

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This AKAP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-143 amino acids from the Central region of human AKAP5.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: AKAP5 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu AKAP5

Target: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Andere Bezeichnung: AKAP5

Hintergrund: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.

Molekulargewicht: 47088

Gen-ID: 9495

NCBI Accession: NP_004848

UniProt: P24588

Pathways: cAMP Metabolic Process