KIF7 Antikörper

Produktnummer ABIN6288850

Produktdetails anti-KIF7 Antikörper

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KIF7 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Verwendungszweck: Kif 7 is a protein encoded by the KIF7 gene which is approximately 150,5 kDa. Kif 7 is localised to the cilium tip. It is involved in signalling by hedgehog and GPCR. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of a ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Kif 7 is expressed in embryonic stem cells and Jurkat T-cells. Mutations in the KIF7 gene may result in Bardet-Biedl syndrome. STJ96965 was developed from clone 3F8 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody detects endogenous Kif 7 proteins.

Spezifität: The antibody detects endogenous Kif 7 proteins.

Produktmerkmale: Mouse monoclonal to Kif 7.

Aufreinigung: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Synthetic Peptide

Klon: 3F8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: IHC 1:200

Kommentare:

Embryonic stem cells, melanotic melanoma and Jurkat T-cells. Expressed in heart, lung, liver, kidney, testis, retina, placenta, pancreas, colon, small intestin, prostate and thymus.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu KIF7

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Andere Bezeichnung: Kif 7 (KIF7 Produkte)

Synonyme: KIF7 antikoerper, DDBDRAFT_0204609 antikoerper, DDBDRAFT_0206583 antikoerper, DDB_0204609 antikoerper, DDB_0206583 antikoerper, ACLS antikoerper, HLS2 antikoerper, JBTS12 antikoerper, UNQ340 antikoerper, cos2 antikoerper, costal2 antikoerper, kinesin family member 7 antikoerper, KIF7 antikoerper, kif7 antikoerper, Kif7 antikoerper

Gen-ID: 374654

UniProt: Q2M1P5

Pathways: Hedgehog Signalweg