KIF7 Antikörper (AA 1044-1343)

Produktnummer ABIN7268137

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch KIF7 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für KIF7 Antikörper (AA 1044-1343) (ABIN7268137)

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KIF7 Antikörper

Bindungsspezifität: AA 1044-1343

Verwendungszweck: KIF7 Rabbit pAb

Sequenz: QLDEAIEALD AAIEYKNEAI TCRQRVLRAS ASLLSQCEMN LMAKLSYLSS SETRALLCKY FDKVVTLREE QHQQQIAFSE LEMQLEEQQR LVYWLEVALE RQRLEMDRQL TLQQKEHEQN MQLLLQQSRD HLGEGLADSR RQYEARIQAL EKELGRYMWI NQELKQKLGG VNAVGHSRGG EKRSLCSEGR QAPGNEDELH LAPELLWLSP LTEGAPRTRE ETRDLVHAPL PLTWKRSSLC GEEQGSPEEL RQREAAEPLV GRVLPVGEAG LPWNFGPLSK PRRELRRASP GMIDVRKNPL

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1044-1343 of human KIF7 (NP_940927.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KIF7

Target: KIF7 (Kinesin Family Member 7 (KIF7))

Andere Bezeichnung: KIF7

Hintergrund: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.,KIF7,ACLS,AGBK,HLS2,JBTS12,UNQ340,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Hedgehog Signaling Pathway,Stem Cells,KIF7

Molekulargewicht: 150kDa

Gen-ID: 374654

UniProt: Q2M1P5

Pathways: Hedgehog Signalweg