COL3A1 Antikörper (N-Term)

Produktnummer ABIN6287750

Produktdetails anti-COL3A1 Antikörper

Target: COL3A1 (Collagen, Type III, alpha 1 (COL3A1))

Bindungsspezifität: AA 50-130, N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL3A1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: COL3A1 is a protein encoded by the COL3A1 gene which is approximately 138,5 kDa. COL3A1 is secreted into the extracellular space and matrix. It is involved in collagen chain trimerization, integrin pathway, ERK signalling, phospholipase-C pathway and binding and uptake of ligands by scavenger receptors. It is involved in regulation of cortical development and is a major ligand of ADGRG1 in the developing brain. COL3A1 is expressed in skin, pancreas, bone, liver and lung. Mutations in the COL3A1 gene result in Ehlers-Danlos syndrome and thoracic aortic aneurysms. STJ92388 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of COL3A1 protein.

Spezifität: COL3A1 Polyclonal Antibody detects endogenous levels of COL3A1 protein.

Produktmerkmale: Rabbit polyclonal to COL3A1.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human COL3A1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu COL3A1

Target: COL3A1 (Collagen, Type III, alpha 1 (COL3A1))

Andere Bezeichnung: COL3A1 (COL3A1 Produkte)

Synonyme: EDS4A antikoerper, AW550625 antikoerper, Col3a-1 antikoerper, MMS10-W antikoerper, Ms10w antikoerper, mKIAA4231 antikoerper, col3a1 antikoerper, collagen type III alpha 1 chain antikoerper, collagen, type III, alpha 1 antikoerper, collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) S homeolog antikoerper, COL3A1 antikoerper, Col3a1 antikoerper, col3a1 antikoerper, col3a1.S antikoerper

Molekulargewicht: 95 kDa

Gen-ID: 1281

UniProt: P02461

Pathways: Autophagie, Growth Factor Binding