COL3A1 Antikörper (C-Term)

Produktnummer ABIN2856819

Produktdetails anti-COL3A1 Antikörper

Target: COL3A1 (Collagen, Type III, alpha 1 (COL3A1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL3A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to Collagen III alpha1 (collagen, type III, alpha 1)
Collagen III alpha1 antibody [C2C3-2], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Collagen III. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: HeLa

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.53 mg/mL

Buffer: 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-COL3A1 Antikörper (ABIN2856819)

Yeh, Chen, Liao, Wu, Huang, Lin: "The Bioactive Core and Corona Synergism of Quantized Gold Enables Slowed Inflammation and Increased Tissue Regeneration in Wound Hypoxia." in: International journal of molecular sciences, Vol. 21, Issue 5, (2020) (PubMed).

Shentu, Huang, Cernelc-Kohan, Chan, Wong, Espinoza, Tan, Gramaglia, van der Heyde, Chien, Hagood: "Thy-1 dependent uptake of mesenchymal stem cell-derived extracellular vesicles blocks myofibroblastic differentiation." in: Scientific reports, Vol. 7, Issue 1, pp. 18052, (2019) (PubMed).

Saito, Chikenji, Ozasa, Fujimiya, Yamashita, Gingery, Iba: "PDGFR Signaling Mediates Hyperproliferation and Fibrotic Responses of Subsynovial Connective Tissue Cells in Idiopathic Carpal Tunnel Syndrome." in: Scientific reports, Vol. 7, Issue 1, pp. 16192, (2019) (PubMed).

Details zu COL3A1

Target: COL3A1 (Collagen, Type III, alpha 1 (COL3A1))

Andere Bezeichnung: collagen type III alpha 1 chain (COL3A1 Produkte)

Synonyme: EDS4A antikoerper, AW550625 antikoerper, Col3a-1 antikoerper, MMS10-W antikoerper, Ms10w antikoerper, mKIAA4231 antikoerper, col3a1 antikoerper, collagen type III alpha 1 chain antikoerper, collagen, type III, alpha 1 antikoerper, collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) S homeolog antikoerper, COL3A1 antikoerper, Col3a1 antikoerper, col3a1 antikoerper, col3a1.S antikoerper

Hintergrund: This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]

Cellular Localization: Secreted , extracellular space , extracellular matrix

Molekulargewicht: 139 kDa

Gen-ID: 1281

UniProt: P02461

Pathways: Autophagie, Growth Factor Binding