CXCR7 Antikörper (C-Term)

Produktnummer ABIN6286163

Produktdetails anti-CXCR7 Antikörper

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Bindungsspezifität: AA 290-370, C-Term

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Verwendungszweck: Rabbit polyclonal to CXCR-7.

Spezifität: CXCR-7 Polyclonal Antibody detects endogenous levels of CXCR-7 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CXCR-7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:20000

Kommentare:

Expressed in monocytes, basophils, B-cells, umbilical vein endothelial cells (HUVEC) and B-lymphoblastoid cells. Lower expression detected in CD4+ T-lymphocytes and natural killer cells. In the brain, detected in endothelial cells and capillaries, and in mature neurons of the frontal cortex and hippocampus. Expressed in tubular formation in the kidney. Highly expressed in astroglial tumor endothelial, microglial and glioma cells. Expressed at low levels in normal CD34+ progenitor cells, but at very high levels in several myeloid malignant cell lines. Expressed in breast carcinomas but not in normal breast tissue (at protein level).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu CXCR7

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Andere Bezeichnung: CXCR-7 (CXCR7 Produkte)

Synonyme: CMKOR1 antikoerper, CXC-R7 antikoerper, CXCR-7 antikoerper, CXCR7 antikoerper, GPR159 antikoerper, RDC-1 antikoerper, RDC1 antikoerper, AW541270 antikoerper, Cmkor1 antikoerper, Cxcr7 antikoerper, Rdc1 antikoerper, ackr3 antikoerper, cxcr7 antikoerper, rdc1 antikoerper, xcxcr7 antikoerper, atypical chemokine receptor 3 antikoerper, ORF 74; similar to Kaposi's sarcoma-associated herpesvirus ORF 74 antikoerper, atypical chemokine receptor 3 L homeolog antikoerper, ACKR3 antikoerper, MmrVgp88 antikoerper, Ackr3 antikoerper, ackr3.L antikoerper

Molekulargewicht: 41 kDa

Gen-ID: 57007

UniProt: P25106

Pathways: Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling