INPP5D Antikörper (C-Term)
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- Target Alle INPP5D Antikörper anzeigen
- INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
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Bindungsspezifität
- AA 1110-1190, C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser INPP5D Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Verwendungszweck
- SHIP-1 is a protein encoded by the INPP5D gene which is approximately 133,3 kDa. SHIP-1 is localised to the cytoplasm and cell membrane. It is involved in inositol phosphate metabolism, RET signalling, B cell receptor signalling pathway and cell surface interactions at the vascular wall. This protein falls under the inositol polyphosphate-5-phosphatase family. It functions as a negative regulator of myeloid cell proliferation and survival. SHIP-1 is specifically expressed in immune and hematopoietic cells. Mutations in the INPP5D gene result in cancers of the immune system. STJ95655 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of SHIP-1 protein.
- Spezifität
- SHIP-1 Polyclonal Antibody detects endogenous levels of SHIP-1 protein.
- Produktmerkmale
- Rabbit polyclonal to SHIP-1.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from human SHIP-1
- Isotyp
- IgG
- Top Product
- Discover our top product INPP5D Primärantikörper
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- Applikationshinweise
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WB 1:500-1:2000
ELISA 1:40000 - Kommentare
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Specifically expressed in immune and hematopoietic cells. Expressed in bone marrow and blood cells. Levels vary considerably within this compartment. Present in at least 74% of immature CD34+ cells, whereas within the more mature population of CD33+ cells, it is present in only 10% of cells. Present in the majority of T-cells, while it is present in a minority of B-cells (at protein level).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Target
- INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
- Andere Bezeichnung
- SHIP-1 (INPP5D Produkte)
- Synonyme
- INPP5D antikoerper, 256.t00004 antikoerper, 13.t00027 antikoerper, ship antikoerper, ship1 antikoerper, AI323613 antikoerper, SHIP antikoerper, SHIP-1 antikoerper, SHIP1 antikoerper, s-SHIP antikoerper, SIP-145 antikoerper, hp51CN antikoerper, inositol polyphosphate-5-phosphatase D antikoerper, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 antikoerper, inositol polyphosphate 5-phosphatase antikoerper, inositol polyphosphate-5-phosphatase D L homeolog antikoerper, INPP5D antikoerper, LOC100446045 antikoerper, inpp5d antikoerper, EHI_159880 antikoerper, EHI_153490 antikoerper, inpp5d.L antikoerper, LOC100380693 antikoerper, Inpp5d antikoerper
- Molekulargewicht
- 133 kDa
- Gen-ID
- 3635
- UniProt
- Q92835
- Pathways
- T-Zell Rezeptor Signalweg, BCR Signaling, Warburg Effekt
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