WNT7A Antikörper (Internal Region)

Produktnummer ABIN6266046

Produktdetails anti-WNT7A Antikörper

Target: WNT7A (Wingless-Type MMTV Integration Site Family, Member 7A (WNT7A))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT7A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: Wnt7a Antibody detects endogenous levels of total Wnt7a.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Wnt7a, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu WNT7A

Target: WNT7A (Wingless-Type MMTV Integration Site Family, Member 7A (WNT7A))

Andere Bezeichnung: WNT7A (WNT7A Produkte)

Synonyme: wnt7a antikoerper, AI849442 antikoerper, Wnt-7a antikoerper, px antikoerper, tw antikoerper, Xwnt-7a antikoerper, wnt-7a antikoerper, wnt7a-A antikoerper, Wnt family member 7A antikoerper, wingless-type MMTV integration site family, member 7Aa antikoerper, wingless-type MMTV integration site family, member 7A antikoerper, wingless-type MMTV integration site family member 7A S homeolog antikoerper, WNT7A antikoerper, wnt7aa antikoerper, Wnt7a antikoerper, wnt7a.S antikoerper

Hintergrund:

Description: Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development (PubMed:16826533). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal neural stem cell proliferation in the hippocampus dentate gyrus. Required for normal progress through the cell cycle in neural progenitor cells, for self-renewal of neural stem cells, and for normal neuronal differentiation and maturation. Promotes formation of synapses via its interaction with FZD5 (By similarity).

Gene: WNT7A

Molekulargewicht: 39kDa

Gen-ID: 7476

UniProt: O00755

Pathways: WNT Signalweg, Stem Cell Maintenance, Asymmetric Protein Localization