TXNRD1 Antikörper (Internal Region)

Produktnummer ABIN6265818

Produktdetails anti-TXNRD1 Antikörper

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXNRD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: TXNRD1 Antibody detects endogenous levels of total TXNRD1.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TXNRD1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu TXNRD1

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Andere Bezeichnung: TXNRD1 (TXNRD1 Produkte)

Synonyme: TrxR1 antikoerper, cb682 antikoerper, fb83a08 antikoerper, wu:fb83a08 antikoerper, GB14972 antikoerper, MGC85342 antikoerper, NADPH-dependent thioredoxin reductase C antikoerper, T32G6.20 antikoerper, T32G6_20 antikoerper, GRIM-12 antikoerper, TR antikoerper, TR1 antikoerper, TRXR1 antikoerper, TXNR antikoerper, Tr antikoerper, thioredoxin reductase 1 antikoerper, thioredoxin reductase 1 L homeolog antikoerper, NADPH-dependent thioredoxin reductase C antikoerper, ThioRedoXin Reductase antikoerper, TXNRD1 antikoerper, txnrd1 antikoerper, Trxr-1 antikoerper, txnrd1.L antikoerper, NTRC antikoerper, trxr-1 antikoerper, Txnrd1 antikoerper

Hintergrund:

Description: Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.

Gene: TXNRD1

Molekulargewicht: 55 kDa

Gen-ID: 7296

UniProt: Q16881

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis