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TXNRD1 Antikörper

TXNRD1 Reaktivität: Human WB, IHC (p), IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855577
  • Target Alle TXNRD1 Antikörper anzeigen
    TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
    Reaktivität
    • 43
    • 28
    • 26
    Human
    Wirt
    • 40
    • 5
    • 1
    Kaninchen
    Klonalität
    • 35
    • 11
    Polyklonal
    Konjugat
    • 20
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TXNRD1 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 14
    • 14
    • 12
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Rabbit polyclonal antibody to TrxR1 (thioredoxin reductase 1)
    TrxR1 antibody [N1N3]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human TrxR1. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product TXNRD1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: HepG2

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
    Andere Bezeichnung
    thioredoxin reductase 1 (TXNRD1 Produkte)
    Synonyme
    TrxR1 antikoerper, cb682 antikoerper, fb83a08 antikoerper, wu:fb83a08 antikoerper, GB14972 antikoerper, MGC85342 antikoerper, NADPH-dependent thioredoxin reductase C antikoerper, T32G6.20 antikoerper, T32G6_20 antikoerper, GRIM-12 antikoerper, TR antikoerper, TR1 antikoerper, TRXR1 antikoerper, TXNR antikoerper, Tr antikoerper, thioredoxin reductase 1 antikoerper, thioredoxin reductase 1 L homeolog antikoerper, NADPH-dependent thioredoxin reductase C antikoerper, ThioRedoXin Reductase antikoerper, TXNRD1 antikoerper, txnrd1 antikoerper, Trxr-1 antikoerper, txnrd1.L antikoerper, NTRC antikoerper, trxr-1 antikoerper, Txnrd1 antikoerper
    Hintergrund
    This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.

    Cellular Localization: Cytoplasm , Isoform 4: Cytoplasm , Nucleus , Isoform 5: Cytoplasm
    Molekulargewicht
    71 kDa
    Gen-ID
    7296
    UniProt
    Q16881
    Pathways
    Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
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