TXNRD1 Antikörper (AA 161-647)

Produktnummer ABIN5776265

Der Maus Monoklonal anti-TXNRD1 Antikörper (Klon AT30F1) (ABIN5776265) detektiert spezifisch TXNRD1 in WB, ELISA, ICC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TXNRD1 Antikörper (AA 161-647) (ABIN5776265)

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TXNRD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: AT30F1

Produktdetails anti-TXNRD1 Antikörper

Bindungsspezifität: AA 161-647

Verwendungszweck: Human Thioredoxin Reductase 1/TRXR1 antibody

Aufreinigung: Purified

Immunogen: Recombinant human TXNRD1 (161-647aa) purified from E. coli

Isotyp: IgG2b kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Details zu TXNRD1

Target: TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))

Andere Bezeichnung: Thioredoxin Reductase 1/TRXR1

Hintergrund: TXNRD1, also known as Thioredoxin reductase 1, is a part of a selenium-containing pyridine nucleotidedisulphide oxidoreductase family, which has a conserved catalytic site of Cys-Val-Asn-Val-Gly-Cys. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, AIDS and other autoimmune diseases as well as bacterial infections and parasitic diseases.

NCBI Accession: NP_001087240

Pathways: Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis