TXNRD1 Produkte
(Thioredoxin Reductase 1 (TXNRD1))
Kategorien
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte TXNRD1 Kategorien
TXNRD1 Antikörper
High quality antibodies with extensive validation data.
TXNRD1 ELISA Kits
Reliable ELISA kits for a wide range of species.
TXNRD1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene TXNRD1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (8)
Kat. Nr.
ABIN7432433
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN1386102
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN7259296
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene TXNRD1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962389
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6973702
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959909
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene TXNRD1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1324248
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7125363
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7391732
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren TXNRD1 Produkten
: "Relationship between selenoprotein P and selenocysteine lyase: Insights into selenium metabolism." in: Free radical biology & medicine, Vol. 127, pp. 182-189, (2018) (PubMed).: "Monitoring thioredoxin redox with a genetically encoded red fluorescent biosensor." in: Nature chemical biology, Vol. 13, Issue 9, pp. 1045-1052, (2017) (PubMed).
: "Intratumoral hemorrhage-related differences in the expression of vascular endothelial growth factor, basic fibroblast growth factor and thioredoxin reductase 1 in human glioblastoma." in: Molecular and clinical oncology, Vol. 5, Issue 4, pp. 343-346, (2016) (PubMed).
: "The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition." in: PLoS ONE, Vol. 11, Issue 1, pp. e0147773, (2016) (PubMed).
: "Thioredoxin reductase as a novel molecular target for cancer therapy." in: Cancer letters, Vol. 236, Issue 2, pp. 164-74, (2006) (PubMed).
: "On the potential of thioredoxin reductase inhibitors for cancer therapy." in: Seminars in cancer biology, Vol. 16, Issue 6, pp. 452-65, (2006) (PubMed).
: "Thioredoxin reductase." in: The Biochemical journal, Vol. 346 Pt 1, pp. 1-8, (2000) (PubMed).
: "Cloning and sequencing of a human thioredoxin reductase." in: FEBS letters, Vol. 373, Issue 1, pp. 5-9, (1995) (PubMed).
Synonyme und alternative Namen zu TXNRD1
thioredoxin reductase 1 (TXNRD1), thioredoxin reductase 1 (txnrd1), thioredoxin reductase 1 (Trxr-1), thioredoxin reductase 1 L homeolog (txnrd1.L), NADPH-dependent thioredoxin reductase C (NTRC), ThioRedoXin Reductase (trxr-1), thioredoxin reductase 1 (Txnrd1), cb682, fb83a08, GB14972, GRIM-12, MGC85342, NADPH-dependent thioredoxin reductase C, T32G6.20, T32G6_20, TR, Tr, TR1, TrxR1, TRXR1, TXNR, wu:fb83a08Bezeichner auf Proteinebene für TXNRD1
- thioredoxin reductase 1, cytoplasmic
- thioredoxin reductase 3
- thioredoxin reductase 1
- thioredoxin reductase 1, cytoplasmic-like
- KM-102-derived reductase-like factor
- gene associated with retinoic and IFN-induced mortality 12 protein
- gene associated with retinoic and interferon-induced mortality 12 protein
- oxidoreductase
- thioredoxin reductase GRIM-12
- thioredoxin reductase TR1
- TR
- redox enzyme thioredoxin reductase
- NADPH-dependent thioredoxin reductase
- selenoprotein oxidoreductase
- TR alpha
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