SMURF1 Antikörper (Internal Region)
-
- Target Alle SMURF1 Antikörper anzeigen
- SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))
-
Bindungsspezifität
- Internal Region
-
Reaktivität
- Human, Maus
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser SMURF1 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA
- Spezifität
- SMURF1 Antibody detects endogenous levels of total SMURF1.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SMURF1, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product SMURF1 Primärantikörper
-
-
- Applikationshinweise
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
-
- Target
- SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))
- Andere Bezeichnung
- SMURF1 (SMURF1 Produkte)
- Synonyme
- 4930431E10Rik antikoerper, mKIAA1625 antikoerper, RGD1309707 antikoerper, SMAD specific E3 ubiquitin protein ligase 1 antikoerper, E3 ubiquitin-protein ligase SMURF1 antikoerper, SMAD specific E3 ubiquitin protein ligase 1 L homeolog antikoerper, SMURF1 antikoerper, LOC100540915 antikoerper, smurf1 antikoerper, Smurf1 antikoerper, smurf1.L antikoerper
- Hintergrund
-
Description: E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Promotes ubiquitination and subsequent proteasomal degradation of MAVS (PubMed:23087404). Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Gene: SMURF1
- Molekulargewicht
- 86 kDa
- Gen-ID
- 57154
- UniProt
- Q9HCE7
- Pathways
- Regulation of Cell Size
-