SMURF1 Antikörper (AA 165-268)

Produktnummer ABIN566098

Produktdetails anti-SMURF1 Antikörper

Target: SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

Bindungsspezifität: AA 165-268

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SMURF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunoprecipitation (IP)

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant SMURF1.

Sequenz: DSGPGRPLSC FMEEPAPYTD STGAAAGGGN CRFVESPSQD QRLQAQRLRN PDVRGSLQTP QNRPHGHQSP ELPEGYEQRT TVQGQVYFLH TQTGVSTWHD PRIP

Kreuzreaktivität: Human, Maus

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: SMURF1 (NP_065162, 165 a.a. ~ 268 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 1D7

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-SMURF1 Antikörper (ABIN566098)

Wang, Zhang, Weng, Qiao, Ma, Xiao, Yu, Pan, Sun et al.: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).

Murakami, Mathew, Huang, Farahani, Peng, Olson, Etlinger: "Smurf1 ubiquitin ligase causes downregulation of BMP receptors and is induced in monocrotaline and hypoxia models of pulmonary arterial hypertension." in: Experimental biology and medicine (Maywood, N.J.), Vol. 235, Issue 7, pp. 805-13, (2010) (PubMed).

Details zu SMURF1

Target: SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

Andere Bezeichnung: SMURF1 (SMURF1 Produkte)

Synonyme: 4930431E10Rik antikoerper, mKIAA1625 antikoerper, RGD1309707 antikoerper, SMAD specific E3 ubiquitin protein ligase 1 antikoerper, E3 ubiquitin-protein ligase SMURF1 antikoerper, SMAD specific E3 ubiquitin protein ligase 1 L homeolog antikoerper, SMURF1 antikoerper, LOC100540915 antikoerper, smurf1 antikoerper, Smurf1 antikoerper, smurf1.L antikoerper

Hintergrund: Full Gene Name: SMAD specific E3 ubiquitin protein ligase 1
Synonyms: KIAA1625

Gen-ID: 57154

NCBI Accession: NM_020429

Pathways: Regulation of Cell Size