SF3B1 Antikörper (N-Term)
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- Target Alle SF3B1 Antikörper anzeigen
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SF3B1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- SAP 155 Antibody detects endogenous levels of total SAP 155.
- Homologie
- Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human SAP 155, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product SF3B1 Primärantikörper
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- Applikationshinweise
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
- Andere Bezeichnung
- SF3B1 (SF3B1 Produkte)
- Synonyme
- Cus1 antikoerper, SAP145 antikoerper, SF3B145 antikoerper, SF3b1 antikoerper, SF3b150 antikoerper, Hsh155 antikoerper, MDS antikoerper, PRP10 antikoerper, PRPF10 antikoerper, SAP155 antikoerper, SF3b155 antikoerper, 155kDa antikoerper, 2810001M05Rik antikoerper, AA409119 antikoerper, Prp10 antikoerper, TA-8 antikoerper, Targ4 antikoerper, hsh155 antikoerper, prp10 antikoerper, prpf10 antikoerper, sap155 antikoerper, SF3B1 antikoerper, Sap155 antikoerper, wu:fb99f09 antikoerper, splicing factor 3b subunit 2 antikoerper, splicing factor 3b subunit 1 antikoerper, splicing factor 3b, subunit 1 antikoerper, splicing factor 3b subunit 1 S homeolog antikoerper, SF3B2 antikoerper, SF3B1 antikoerper, Sf3b1 antikoerper, sf3b1.S antikoerper, sf3b1 antikoerper
- Hintergrund
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Description: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937). May also be involved in the assembly of the 'E' complex (PubMed:10882114). Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (PubMed:15146077).
Gene: SF3B1
- Molekulargewicht
- 145 kDa
- Gen-ID
- 23451
- UniProt
- O75533
- Pathways
- Chromatin Binding
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