MAP3K11 Antikörper (Internal Region)

Produktnummer ABIN6263276

Produktdetails anti-MAP3K11 Antikörper

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: MLK3 Antibody detects endogenous levels of total MLK3.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MLK3, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MAP3K11

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Andere Bezeichnung: MAP3K11 (MAP3K11 Produkte)

Synonyme: MEKK11 antikoerper, MLK-3 antikoerper, MLK3 antikoerper, PTK1 antikoerper, SPRK antikoerper, 2610017K16Rik antikoerper, Mlk3 antikoerper, Mlk-3 antikoerper, RHOE antikoerper, mitogen-activated protein kinase kinase kinase 11 antikoerper, MAP3K11 antikoerper, Map3k11 antikoerper

Hintergrund:

Description: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

Gene: MAP3K11

Molekulargewicht: 92kDa

Gen-ID: 4296

UniProt: Q16584

Pathways: MAPK Signalweg, Interferon-gamma Pathway