MAP3K11 Antikörper (AA 536-693)

Produktnummer ABIN7160017

Produktdetails anti-MAP3K11 Antikörper

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Bindungsspezifität: AA 536-693

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K11 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Mitogen-activated protein kinase kinase kinase 11 protein (536-693AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MAP3K11

Target: MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))

Andere Bezeichnung: MAP3K11 (MAP3K11 Produkte)

Synonyme: MEKK11 antikoerper, MLK-3 antikoerper, MLK3 antikoerper, PTK1 antikoerper, SPRK antikoerper, 2610017K16Rik antikoerper, Mlk3 antikoerper, Mlk-3 antikoerper, RHOE antikoerper, mitogen-activated protein kinase kinase kinase 11 antikoerper, MAP3K11 antikoerper, Map3k11 antikoerper

Hintergrund:

Background: Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.

Aliases: 2610017K16Rik antibody, EC 2.7.11.25 antibody, M3K11_HUMAN antibody, Map3k11 antibody, MEKK11 antibody, MGC17114 antibody, Mitogen-activated protein kinase kinase kinase 11 antibody, Mixed lineage kinase 3 antibody, Mixed lineage protein kinase 3 antibody, Mlk-3 antibody, Mlk3 antibody, Protein tyrosine kinase PTK1 antibody, PTK1 antibody, RHOE antibody, SH3 domain containing proline rich kinase antibody, SPRK antibody, Src-homology 3 domain-containing proline-rich kinase antibody

UniProt: Q16584

Pathways: MAPK Signalweg, Interferon-gamma Pathway