MCM5 Antikörper (N-Term)

Produktnummer ABIN6263165

Produktdetails anti-MCM5 Antikörper

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Spezifität: MCM5 Antibody detects endogenous levels of total MCM5.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human MCM5, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu MCM5

Target: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Andere Bezeichnung: MCM5 (MCM5 Produkte)

Synonyme: 23.m06024 antikoerper, cdc46 antikoerper, xmcm5 antikoerper, CDC46 antikoerper, P1-CDC46 antikoerper, Afu5g02520 antikoerper, NCU01171.1 antikoerper, AA617332 antikoerper, AI324988 antikoerper, AL033333 antikoerper, Cdc46 antikoerper, Mcmd5 antikoerper, mCD46 antikoerper, mCDC46 antikoerper, mcm5 antikoerper, wu:fb34a06 antikoerper, CG4082 antikoerper, DmCDC46 antikoerper, DmCDC465 antikoerper, DmMCM5 antikoerper, DmMcm5 antikoerper, DmeMCM5 antikoerper, Dmel\\CG4082 antikoerper, MCM5 antikoerper, McM5 antikoerper, PCR4 antikoerper, DNA replication licensing factor MCM5 antikoerper, minichromosome maintenance complex component 5 S homeolog antikoerper, minichromosome maintenance complex component 5 antikoerper, DNA replication licensing factor Mcm5 antikoerper, DNA replication licensing factor mcm5 antikoerper, MCM5 minichromosome maintenance deficient 5 (S. cerevisiae) antikoerper, minichromosome maintenance complex component 5 L homeolog antikoerper, Minichromosome maintenance 5 antikoerper, DNA replication licensing factor mcm-5 antikoerper, BBOV_IV010040 antikoerper, mcm5.S antikoerper, MCM5 antikoerper, AFUA_5G02520 antikoerper, NCU01171 antikoerper, PVX_084615 antikoerper, LOC5576119 antikoerper, CpipJ_CPIJ008678 antikoerper, Bm1_24480 antikoerper, CMU_022890 antikoerper, Mcm5 antikoerper, mcm5 antikoerper, TP01_0722 antikoerper, mcm5.L antikoerper, mcm-5 antikoerper

Hintergrund:

Description: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.

Gene: MCM5

Molekulargewicht: 82 kDa

Gen-ID: 4174

UniProt: P33992

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA