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IL1RN Antikörper (Internal Region)

IL1RN Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6262550
  • Target Alle IL1RN Antikörper anzeigen
    IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
    Bindungsspezifität
    • 28
    • 16
    • 11
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 79
    • 33
    • 15
    • 9
    • 9
    • 8
    • 7
    • 4
    • 4
    • 3
    Human, Maus, Ratte
    Wirt
    • 96
    • 34
    • 5
    • 3
    • 1
    • 1
    Kaninchen
    Klonalität
    • 103
    • 37
    Polyklonal
    Konjugat
    • 69
    • 29
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL1RN Antikörper ist unkonjugiert
    Applikation
    • 114
    • 51
    • 36
    • 25
    • 25
    • 21
    • 18
    • 18
    • 13
    • 13
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Spezifität
    IL1RN Antibody detects endogenous levels of total IL1RN.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human IL1RN, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product IL1RN Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))
    Andere Bezeichnung
    IL1RN (IL1RN Produkte)
    Synonyme
    DIRA antikoerper, ICIL-1RA antikoerper, IL-1RN antikoerper, IL-1ra antikoerper, IL-1ra3 antikoerper, IL1F3 antikoerper, IL1RA antikoerper, IRAP antikoerper, MVCD4 antikoerper, IRAP1 antikoerper, IL1RN antikoerper, IL-1RA antikoerper, F630041P17Rik antikoerper, interleukin 1 receptor antagonist antikoerper, interleukin 1 receptor antagonist-like antikoerper, IL1RN antikoerper, Il1rn antikoerper, IL1RNL antikoerper
    Hintergrund

    Description: Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2, however, the physiological relevance of the latter association is unsure.

    Gene: IL1RN

    Molekulargewicht
    20kDa
    Gen-ID
    3557
    UniProt
    P18510
    Pathways
    NF-kappaB Signalweg, Hormone Transport, Cancer Immune Checkpoints
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