HLA-DMB Antikörper (C-Term)

Produktnummer ABIN6262286

Produktdetails anti-HLA-DMB Antikörper

Target: HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HLA-DMB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: HLA-DMB Antibody detects endogenous levels of total HLA-DMB.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HLA-DMB, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu HLA-DMB

Target: HLA-DMB (Major Histocompatibility Complex, Class II, DM beta (HLA-DMB))

Andere Bezeichnung: HLA-DMB (HLA-DMB Produkte)

Synonyme: RING7 antikoerper, D6S221E antikoerper, RT1.DMb antikoerper, RT1.Mb antikoerper, MHC-DMB antikoerper, major histocompatibility complex, class II, DM beta antikoerper, RT1 class II, locus DMb antikoerper, HLA-DMB antikoerper, RT1-DMb antikoerper, PATR-DMB antikoerper

Hintergrund:

Description: Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.

Gene: HLA-DMB

Molekulargewicht: 29 kDa

Gen-ID: 3109

UniProt: P28068

Pathways: Cancer Immune Checkpoints