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PUMA Antikörper (Internal Region)

BBC3 Reaktivität: Human, Ratte, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6260207
  • Target Alle PUMA (BBC3) Antikörper anzeigen
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Bindungsspezifität
    • 16
    • 13
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 95
    • 40
    • 39
    • 16
    Human, Ratte, Maus
    Wirt
    • 92
    • 6
    • 1
    Kaninchen
    Klonalität
    • 82
    • 17
    Polyklonal
    Konjugat
    • 51
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PUMA Antikörper ist unkonjugiert
    Applikation
    • 80
    • 34
    • 31
    • 21
    • 16
    • 14
    • 14
    • 13
    • 9
    • 7
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA
    Spezifität
    BBC3 Antibody detects endogenous levels of total BBC3.
    Homologie
    Pig,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human BBC3(PUMA), corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product BBC3 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Zhang, Li, Wang, Li, Shi, Kan, Pang: "Inhibition of REST Suppresses Proliferation and Migration in Glioblastoma Cells." in: International journal of molecular sciences, Vol. 17, Issue 5, (2017) (PubMed).

  • Target
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Andere Bezeichnung
    BBC3 (BBC3 Produkte)
    Synonyme
    BBC3 antikoerper, Puma antikoerper, JFY-1 antikoerper, JFY1 antikoerper, PUMA antikoerper, PUMA/JFY1 antikoerper, BCL2 binding component 3 antikoerper, Bcl-2 binding component 3 antikoerper, BBC3 antikoerper, Bbc3 antikoerper, bbc3 antikoerper
    Hintergrund

    Description: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.

    Gene: BBC3

    Molekulargewicht
    20 kDa
    Gen-ID
    27113
    UniProt
    Q9BXH1
    Pathways
    p53 Signalweg, Positive Regulation of Endopeptidase Activity
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