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PUMA Antikörper (AA 131-180)

Name: PUMA Antikörper (AA 131-180)
SKU: ABIN731528
Availability: InStock

Es sind 3+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-PUMA Antikörper wird verwendet zum Nachweis von PUMA in Proben von Human. Er wurde validiert für WB, FACS, IP, IHC (p), IF (cc), IF (p) und IHC (fro).

Erianin induced mitochondrial apoptosis in liver cancer cells. (PUMA Antikörper (AA 131-180))

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti BBC3/PUMA Polyclonal Antibody, Unconjugated (ABIN731528) at 1:200 followed by conjugation to the secondary antibody and DAB staining (PUMA Antikörper (AA 131-180))

IHC

K562 lysates probed with PUMA Polyclonal Antibody, unconjugated at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 60 minutes at 37°C. (PUMA Antikörper (AA 131-180))

U87MG cells probed with Puma Polyclonal Antibody, Unconjugated at 1:50 for 30 minutes followed by incubation with a conjugated secondary (PE Conjugated) (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). (PUMA Antikörper (AA 131-180))

FACS

4 Abbildungen

(3 Referenzen)

Produktnummer ABIN731528

-20% for 20 Years of ABO

286,16 €

~~357,70 €~~

Sparen Sie 71,54 € (-20 %)

Zzgl. Versandkosten 20,00 € und MwSt

100 μL

Lieferung nach: Deutschland

Lieferung in 8 bis 12 Werktagen

Kurzübersicht für PUMA Antikörper (AA 131-180) (ABIN731528)

Target

Alle PUMA (BBC3) Antikörper anzeigen

PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Reaktivität

Human

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser PUMA Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

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Bindungsspezifität
23

18

15

8

6

5

5

4

2

2

2

1

1

1

1

1

1

1

1

1
AA 131-180

Verwendungszweck

BBC3/PUMA Polyclonal Antibody

Kreuzreaktivität

Human, Ratte

Homologie

Mouse,Dog,Cow,Pig

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human PUMA

Isotyp

IgG
anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibody
BBC3 Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB01353 unconjugated

anti-BCL2 Binding Component 3 (BBC3) (AA 119-154) antibody
BBC3 Reaktivität: Human WB, ELISA, IHC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-BCL2 Binding Component 3 (BBC3) (AA 109-137) antibody
BBC3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB33714 unconjugated

anti-BCL2 Binding Component 3 (BBC3) (N-Term) antibody
BBC3 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-BCL2 Binding Component 3 (BBC3) (AA 186-199) antibody
BBC3 Reaktivität: Human WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-BCL2 Binding Component 3 (BBC3) (C-Term) antibody
BBC3 Reaktivität: Human, Maus WB, IHC, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-BCL2 Binding Component 3 (BBC3) antibody
BBC3 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB1935 unconjugated Recombinant Antibody

anti-BCL2 Binding Component 3 (BBC3) (AA 2-16) antibody
BBC3 Reaktivität: Human, Ratte, Maus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-BCL2 Binding Component 3 (BBC3) (AA 98-152) antibody
BBC3 Reaktivität: Human ELISA Wirt: Maus Monoclonal 5D10 unconjugated

anti-BCL2 Binding Component 3 (BBC3) (BH3 Domain), (C-Term) antibody
BBC3 Reaktivität: Human, Maus WB, IF, FACS, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB(1:300-5000),

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Su, Shi, Yan, Xi, Su: "Anticancer bioactive peptides suppress human colorectal tumor cell growth and induce apoptosis via modulating the PARP-p53-Mcl-1 signaling pathway." in: Acta pharmacologica Sinica, Vol. 36, Issue 12, pp. 1514-9, (2016) (PubMed).

Qiu, Cai, Gao, Gu, Liu: "A small peptide derived from p53 linker region can resume the apoptotic activity of p53 by sequestering iASPP with p53." in: Cancer letters, Vol. 356, Issue 2 Pt B, pp. 910-7, (2014) (PubMed).

Zhang, Liu, Xia, Zhang, Zhang, Zhao, Chao, Jiang, Jiang: "Epithelial-mesenchymal transition is necessary for acquired resistance to cisplatin and increases the metastatic potential of nasopharyngeal carcinoma cells." in: International journal of molecular medicine, Vol. 33, Issue 1, pp. 151-9, (2013) (PubMed).
Target

PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))

Andere Bezeichnung

PUMA

Hintergrund

Synonyms: JFY1, PUMA, JFY-1, Bcl-2-binding component 3, p53 up-regulated modulator of apoptosis, BBC3
Background: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Isoform 3 fails to show any growth-inhibitory or apoptotic activity.

Gen-ID

27113

UniProt

Q96PG8

Pathways

p53 Signalweg, Positive Regulation of Endopeptidase Activity