TFAP2A Antikörper

Produktnummer ABIN6259961

Produktdetails anti-TFAP2A Antikörper

Target: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFAP2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität: AP-2 Antibody detects endogenous levels of AP-2

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AP-2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Referenzen für anti-TFAP2A Antikörper (ABIN6259961)

Yang, Wei, Song, Cai, Zhou, Peng, Jiang, Peng: "E4BP4 mediates glucocorticoid-regulated adipogenesis through COX2." in: Molecular and cellular endocrinology, Vol. 450, pp. 43-53, (2018) (PubMed).

Details zu TFAP2A

Target: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Andere Bezeichnung: AP-2 (TFAP2A Produkte)

Synonyme: TFAP2A antikoerper, Ap-2 antikoerper, AP-2 antikoerper, AP-2alpha antikoerper, AP2TF antikoerper, BOFS antikoerper, TFAP2 antikoerper, ap2 antikoerper, xap2 antikoerper, XAP-2 antikoerper, ap2tf antikoerper, tfap2 antikoerper, ap-2alpha antikoerper, tfap2alpha antikoerper, cb93 antikoerper, fb83f04 antikoerper, fc31a07 antikoerper, wu:fb83f04 antikoerper, wu:fc31a07 antikoerper, tfap2a-a antikoerper, tcfap2a antikoerper, ap2a antikoerper, AP2alpha antikoerper, Ap2 antikoerper, Ap2tf antikoerper, Tcfap2a antikoerper, AP2 antikoerper, transcription factor AP-2 alpha antikoerper, transcription factor AP-2 antikoerper, tto transcription factor AP-2 alpha antikoerper, to transcription factor AP-2 alpha L homeolog antikoerper, to transcription factor AP-2 alpha S homeolog antikoerper, Transcription factor AP-2 alpha antikoerper, transcription factor AP-2, alpha antikoerper, TFAP2A antikoerper, LOC100302602 antikoerper, tfap2a antikoerper, tfap2a.L antikoerper, tfap2a.S antikoerper, ap2a antikoerper, Tfap2a antikoerper

Hintergrund:

Description: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.

Gene: TFAP2A

Molekulargewicht: 49kDa

Gen-ID: 7020

UniProt: P05549, Q92481

Pathways: Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Response to Water Deprivation, Sensory Perception of Sound, Tube Formation, Embryonic Body Morphogenesis, Brown Fat Cell Differentiation, Lipid Metabolism