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TFAP2A Antikörper (N-Term)

TFAP2A Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB12671 unconjugated
Produktnummer ABIN1882156
  • Target Alle TFAP2A Antikörper anzeigen
    TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))
    Bindungsspezifität
    • 11
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 104-133, N-Term
    Reaktivität
    • 55
    • 20
    • 17
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 38
    • 17
    • 3
    Kaninchen
    Klonalität
    • 40
    • 18
    Polyklonal
    Konjugat
    • 34
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser TFAP2A Antikörper ist unkonjugiert
    Applikation
    • 43
    • 29
    • 11
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    B, M, Rat, Sh
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This AP2 alpha antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human AP2 alpha.
    Klon
    RB12671
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TFAP2A Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Semenza: "Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1." in: The Biochemical journal, Vol. 405, Issue 1, pp. 1-9, (2007) (PubMed).

    Provenzano, Yu, Hitchler, Fitzgerald, Robinson, Wayne, Ver Meer, Domann: "AP-2 participates in the transcriptional control of the amyloid precursor protein (APP) gene in oral squamous cell carcinoma." in: Experimental and molecular pathology, Vol. 83, Issue 2, pp. 277-82, (2007) (PubMed).

    Han, Ritzenthaler, Wingerd, Rivera, Roman: "Extracellular matrix fibronectin increases prostaglandin E2 receptor subtype EP4 in lung carcinoma cells through multiple signaling pathways: the role of AP-2." in: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 7961-72, (2007) (PubMed).

  • Target
    TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))
    Andere Bezeichnung
    AP2 alpha (TFAP2A Produkte)
    Synonyme
    TFAP2A antikoerper, Ap-2 antikoerper, AP-2 antikoerper, AP-2alpha antikoerper, AP2TF antikoerper, BOFS antikoerper, TFAP2 antikoerper, ap2 antikoerper, xap2 antikoerper, XAP-2 antikoerper, ap2tf antikoerper, tfap2 antikoerper, ap-2alpha antikoerper, tfap2alpha antikoerper, cb93 antikoerper, fb83f04 antikoerper, fc31a07 antikoerper, wu:fb83f04 antikoerper, wu:fc31a07 antikoerper, tfap2a-a antikoerper, tcfap2a antikoerper, ap2a antikoerper, AP2alpha antikoerper, Ap2 antikoerper, Ap2tf antikoerper, Tcfap2a antikoerper, AP2 antikoerper, transcription factor AP-2 alpha antikoerper, transcription factor AP-2 antikoerper, tto transcription factor AP-2 alpha antikoerper, to transcription factor AP-2 alpha L homeolog antikoerper, to transcription factor AP-2 alpha S homeolog antikoerper, Transcription factor AP-2 alpha antikoerper, transcription factor AP-2, alpha antikoerper, TFAP2A antikoerper, LOC100302602 antikoerper, tfap2a antikoerper, tfap2a.L antikoerper, tfap2a.S antikoerper, ap2a antikoerper, Tfap2a antikoerper
    Hintergrund
    Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle.
    Molekulargewicht
    48062
    NCBI Accession
    NP_001027451, NP_001035890, NP_003211
    UniProt
    P05549
    Pathways
    Caspase Kaskade in der Apoptose, EGFR Signaling Pathway, Response to Water Deprivation, Sensory Perception of Sound, Tube Formation, Embryonic Body Morphogenesis, Brown Fat Cell Differentiation, Lipid Metabolism
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