PPP2R2B Antikörper (Internal Region)

Produktnummer ABIN6259158

Produktdetails anti-PPP2R2B Antikörper

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: PPP2R2B Antibody detects endogenous levels of total PPP2R2B.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PPP2R2B, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PPP2R2B

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Andere Bezeichnung: PPP2R2B (PPP2R2B Produkte)

Synonyme: B55BETA antikoerper, PP2AB55BETA antikoerper, PP2ABBETA antikoerper, PP2APR55B antikoerper, PP2APR55BETA antikoerper, PR2AB55BETA antikoerper, PR2ABBETA antikoerper, PR2APR55BETA antikoerper, PR52B antikoerper, PR55-BETA antikoerper, PR55BETA antikoerper, SCA12 antikoerper, Pppr2b2 antikoerper, 2900026H06Rik antikoerper, 6330404L05Rik antikoerper, E130009M08Rik antikoerper, PP2A-PR55B antikoerper, PP2A antikoerper, ppp2r2b-a antikoerper, ppp2r2c antikoerper, ppp2r2b antikoerper, zgc:101861 antikoerper, PPP2R2B antikoerper, protein phosphatase 2 regulatory subunit Bbeta antikoerper, protein phosphatase 2, regulatory subunit B, beta antikoerper, protein phosphatase 2 regulatory subunit B, beta L homeolog antikoerper, protein phosphatase 2 regulatory subunit B, beta antikoerper, protein phosphatase 2, regulatory subunit B, beta b antikoerper, PPP2R2B antikoerper, Ppp2r2b antikoerper, ppp2r2b.L antikoerper, ppp2r2b antikoerper, ppp2r2bb antikoerper

Hintergrund:

Description: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity).

Gene: PPP2R2B

Molekulargewicht: 51 kDa

Gen-ID: 5521

UniProt: Q00005

Pathways: PI3K-Akt Signalweg, Mitotic G1-G1/S Phases, Hepatitis C