PPP2R2B Antikörper (AA 160-260)

Produktnummer ABIN6146087

Produktdetails anti-PPP2R2B Antikörper

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Bindungsspezifität: AA 160-260

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KIRWLPQQNA AYFLLSTNDK TVKLWKVSER DKRPEGYNLK DEEGRLRDPA TITTLRVPVL RPMDLMVEAT PRRVFANAHT YHINSISVNS DYETYMSADD L

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-260 of human PP2A-B55beta/PR55beta/PP2A-B55beta/PR55beta/PPP2R2B (NP_858060.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PPP2R2B

Target: PPP2R2B (Protein Phosphatase 2, Regulatory Subunit B, beta (PPP2R2B))

Andere Bezeichnung: PPP2R2B (PPP2R2B Produkte)

Synonyme: B55BETA antikoerper, PP2AB55BETA antikoerper, PP2ABBETA antikoerper, PP2APR55B antikoerper, PP2APR55BETA antikoerper, PR2AB55BETA antikoerper, PR2ABBETA antikoerper, PR2APR55BETA antikoerper, PR52B antikoerper, PR55-BETA antikoerper, PR55BETA antikoerper, SCA12 antikoerper, Pppr2b2 antikoerper, 2900026H06Rik antikoerper, 6330404L05Rik antikoerper, E130009M08Rik antikoerper, PP2A-PR55B antikoerper, PP2A antikoerper, ppp2r2b-a antikoerper, ppp2r2c antikoerper, ppp2r2b antikoerper, zgc:101861 antikoerper, PPP2R2B antikoerper, protein phosphatase 2 regulatory subunit Bbeta antikoerper, protein phosphatase 2, regulatory subunit B, beta antikoerper, protein phosphatase 2 regulatory subunit B, beta L homeolog antikoerper, protein phosphatase 2 regulatory subunit B, beta antikoerper, protein phosphatase 2, regulatory subunit B, beta b antikoerper, PPP2R2B antikoerper, Ppp2r2b antikoerper, ppp2r2b.L antikoerper, ppp2r2b antikoerper, ppp2r2bb antikoerper

Hintergrund: The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 55-78 copies in cases of SCA12.,PPP2R2B,B55BETA,PP2AB55BETA,PP2ABBETA,PP2APR55B,PP2APR55BETA,PR2AB55BETA,PR2ABBETA,PR2APR55BETA,PR52B,PR55-BETA,PR55BETA,SCA12,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Centromere,Wnt/β-Catenin Signaling Pathway,Neuroscience,Neurodegenerative Diseases,PPP2R2B

Molekulargewicht: 50 kDa/51 kDa/52 kDa/58 kDa/62 kDa

Gen-ID: 5521

UniProt: Q00005

Pathways: PI3K-Akt Signalweg, Mitotic G1-G1/S Phases, Hepatitis C