IL12RB1 Antikörper (Internal Region)

Produktnummer ABIN6259088

Produktdetails anti-IL12RB1 Antikörper

Target: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL12RB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: IL12RB1 Antibody detects endogenous levels of total IL12RB1.

Homologie: Bovine

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IL12RB1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu IL12RB1

Target: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Andere Bezeichnung: IL12RB1 (IL12RB1 Produkte)

Synonyme: Il12rb antikoerper, IL12RB1 antikoerper, IL-12R antikoerper, CD212 antikoerper, IL-12R-BETA1 antikoerper, IL12RB antikoerper, IL-12R[b] antikoerper, interleukin 12 receptor subunit beta 1 antikoerper, interleukin 12 receptor, beta 1 antikoerper, Il12rb1 antikoerper, IL12RB1 antikoerper

Hintergrund:

Description: Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Gene: IL12RB1

Molekulargewicht: 73 kDa

Gen-ID: 3594

UniProt: P42701

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation