IL12RB1 Antikörper (AA 420-470)

Produktnummer ABIN747863

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-IL12RB1 Antikörper wird verwendet zum Nachweis von IL12RB1 in Proben von Maus. Er wurde validiert für WB, IF (cc), IF (p), IHC (fro) und IHC (p).

Kurzübersicht für IL12RB1 Antikörper (AA 420-470) (ABIN747863)

Target: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL12RB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-IL12RB1 Antikörper

Bindungsspezifität: AA 420-470

Verwendungszweck: IL12RB1 Polyclonal Antibody

Kreuzreaktivität: Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse IL-12RB1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-IL12RB1 Antikörper (ABIN747863)

Terayama, Yoshimoto, Hirai, Naito, Qu, Hatayama, Hayashi, Mitobe, Furusawa, Mizoguchi, Kezuka, Goto, Suyama, Moriyama, Sakabe, Itoh: "Contribution of IL-12/IL-35 common subunit p35 to maintaining the testicular immune privilege." in: PLoS ONE, Vol. 9, Issue 4, pp. e96120, (2014) (PubMed).

Details zu IL12RB1

Target: IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

Andere Bezeichnung: Il-12rb1/Cd212

Hintergrund:

Synonyms: CD212, IL-12R[b], Interleukin-12 receptor subunit beta-1, IL-12 receptor subunit beta-1, IL-12R subunit beta-1, IL-12R-beta-1, IL-12 receptor beta component, Il12rb1, Il12rb

Background: Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Gen-ID: 16161

UniProt: Q60837

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation