RGS1 Antikörper (Internal Region)

Produktnummer ABIN6258912

Produktdetails anti-RGS1 Antikörper

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: RGS1 Antibody detects endogenous levels of total RGS1.

Homologie: Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human RGS1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu RGS1

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Andere Bezeichnung: RGS1 (RGS1 Produkte)

Synonyme: 1R20 antikoerper, BL34 antikoerper, IER1 antikoerper, IR20 antikoerper, RGS1 antikoerper, 1r20 antikoerper, bl34 antikoerper, ier1 antikoerper, ir20 antikoerper, regulator of G protein signaling 1 antikoerper, regulator of G-protein signaling 1 antikoerper, regulator of G-protein signaling 1 S homeolog antikoerper, Regulator of G-protein signaling 1 antikoerper, RGS1 antikoerper, Rgs1 antikoerper, rgs1.S antikoerper, rgs1 antikoerper

Hintergrund:

Description: Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors (PubMed:10480894). Inhibits B cell chemotaxis toward CXCL12 (By similarity). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (PubMed:10480894, PubMed:18434541).

Gene: RGS1

Molekulargewicht: 22 kDa

Gen-ID: 5996

UniProt: Q08116

Pathways: MAPK Signalweg, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events