RGS1 Antikörper (N-Term)

Produktnummer ABIN652704

Produktdetails anti-RGS1 Antikörper

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Bindungsspezifität: AA 19-45, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RGS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human RGS1.

Klon: RB22894

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu RGS1

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Andere Bezeichnung: RGS1 (RGS1 Produkte)

Synonyme: 1R20 antikoerper, BL34 antikoerper, IER1 antikoerper, IR20 antikoerper, RGS1 antikoerper, 1r20 antikoerper, bl34 antikoerper, ier1 antikoerper, ir20 antikoerper, regulator of G protein signaling 1 antikoerper, regulator of G-protein signaling 1 antikoerper, regulator of G-protein signaling 1 S homeolog antikoerper, Regulator of G-protein signaling 1 antikoerper, RGS1 antikoerper, Rgs1 antikoerper, rgs1.S antikoerper, rgs1 antikoerper

Hintergrund: RGS1 is a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Molekulargewicht: 23858

Gen-ID: 5996

NCBI Accession: NP_002913

UniProt: Q08116

Pathways: MAPK Signalweg, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events