RGS1 Antikörper (AA 90-170)

Produktnummer ABIN7216822

Der Kaninchen Polyklonal anti-RGS1 Antikörper (ABIN7216822) detektiert spezifisch RGS1 in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für RGS1 Antikörper (AA 90-170) (ABIN7216822)

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-RGS1 Antikörper

Bindungsspezifität: AA 90-170

Verwendungszweck: Rabbit Anti-RGS1 Polyclonal Antibody

Spezifität: RGS1 Polyclonal Antibody detects endogenous levels of RGS1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human RGS1 at AA range: 90-170

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RGS1

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Andere Bezeichnung: RGS1

Hintergrund: RGS1, 1R20, BL34, IER1, Regulator of G-protein signaling 1, RGS1, B-cell activation protein BL34, Early response protein 1R20RGS1 encodes a member of the regulator of G-protein signalling family. Regulator of G-protein signaling 1 is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Molekulargewicht: 22kD

Gen-ID: 5996

UniProt: Q08116

Pathways: MAPK Signalweg, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events