ZFPM1 Antikörper (Internal Region)

Produktnummer ABIN6257555

Produktdetails anti-ZFPM1 Antikörper

Target: ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFPM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: ZFPM1 Antibody detects endogenous levels of total ZFPM1.

Homologie: Pig

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ZFPM1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu ZFPM1

Target: ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))

Andere Bezeichnung: ZFPM1 (ZFPM1 Produkte)

Synonyme: FOG antikoerper, FOG1 antikoerper, ZC2HC11A antikoerper, ZNF408 antikoerper, ZNF89A antikoerper, Fog1 antikoerper, Xfog antikoerper, fog antikoerper, fog-1 antikoerper, fog1 antikoerper, FOG-1 antikoerper, si:dkey-20g6.1 antikoerper, si:dkey-38l12.1 antikoerper, ZNF469 antikoerper, ZFPM1 antikoerper, zinc finger protein, FOG family member 1 antikoerper, zinc finger protein, multitype 1 antikoerper, zinc finger protein, FOG family member 1 L homeolog antikoerper, ZFPM1 antikoerper, Zfpm1 antikoerper, zfpm1.L antikoerper, zfpm1 antikoerper

Hintergrund:

Description: Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2 (By similarity).

Gene: ZFPM1

Molekulargewicht: 104 kDa

Gen-ID: 161882

UniProt: Q8IX07