ZFPM1 Antikörper (C-Term)

Produktnummer ABIN6242705

Produktdetails anti-ZFPM1 Antikörper

Target: ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))

Bindungsspezifität: AA 954-987, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFPM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZFPM1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 954-987 amino acids from the C-terminal region of human ZFPM1.

Klon: RB51246

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu ZFPM1

Target: ZFPM1 (Zinc Finger Protein, Multitype 1 (ZFPM1))

Andere Bezeichnung: ZFPM1 (ZFPM1 Produkte)

Synonyme: FOG antikoerper, FOG1 antikoerper, ZC2HC11A antikoerper, ZNF408 antikoerper, ZNF89A antikoerper, Fog1 antikoerper, Xfog antikoerper, fog antikoerper, fog-1 antikoerper, fog1 antikoerper, FOG-1 antikoerper, si:dkey-20g6.1 antikoerper, si:dkey-38l12.1 antikoerper, ZNF469 antikoerper, ZFPM1 antikoerper, zinc finger protein, FOG family member 1 antikoerper, zinc finger protein, multitype 1 antikoerper, zinc finger protein, FOG family member 1 L homeolog antikoerper, ZFPM1 antikoerper, Zfpm1 antikoerper, zfpm1.L antikoerper, zfpm1 antikoerper

Hintergrund: Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2 (By similarity).

Molekulargewicht: 104888

UniProt: Q8IX07