PTPN1 Antikörper (pSer50)
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- Target Alle PTPN1 Antikörper anzeigen
- PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))
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Bindungsspezifität
- pSer50
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PTPN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Phospho-PTP1B (Ser50) Antibody detects endogenous levels of PTP1B only when phosphorylated at Serine 50.
- Homologie
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
- Immunogen
- A synthesized peptide derived from human PTP1B around the phosphorylation site of Ser50.
- Isotyp
- IgG
- Top Product
- Discover our top product PTPN1 Primärantikörper
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anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 40-246) antibody
PTPN1 Reaktivität: Human WB, ELISA, IHC, FACS, ICC Wirt: Maus Monoclonal 4F8F11 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) antibodyPTPN1 Reaktivität: Human, Affe, Hund WB, IHC, FACS, IF, IHC (p) Wirt: Maus Monoclonal 1D10 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) antibodyKO Validated PTPN1 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 1-100) antibodyPTPN1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) antibodyPTPN1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Monoclonal 1G3 unconjugated Recombinant Antibody
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 40-246) antibodyPTPN1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4F8F2 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (N-Term) antibodyPTPN1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 268-406) antibodyPTPN1 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 23-53), (N-Term) antibodyPTPN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB7011 unconjugated
anti-Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1) (AA 221-249) antibodyPTPN1 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB41801 unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))
- Andere Bezeichnung
- PTPN1 (PTPN1 Produkte)
- Synonyme
- PTPN1 antikoerper, PTP1B antikoerper, PTP-1B antikoerper, PTP-HA2 antikoerper, Ptp antikoerper, ptp1b antikoerper, wu:fk54h03 antikoerper, CPTP1 antikoerper, protein tyrosine phosphatase, non-receptor type 1 antikoerper, protein tyrosine phosphatase, non-receptor type 1 L homeolog antikoerper, PTPN1 antikoerper, Ptpn1 antikoerper, ptpn1 antikoerper, ptpn1.L antikoerper
- Hintergrund
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Description: Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK, inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
Gene: PTPN1
- Molekulargewicht
- 49kDa
- Gen-ID
- 5770
- UniProt
- P18031
- Pathways
- TLR Signalweg, Response to Growth Hormone Stimulus, ER-Nucleus Signaling, Platelet-derived growth Factor Receptor Signaling
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