Tyrosinase-Related Protein 1 Antikörper

Produktnummer ABIN6252896

Produktdetails anti-Tyrosinase-Related Protein 1 Antikörper

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Tyrosinase-Related Protein 1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Protein G affinity chromatography

Immunogen: Recombinant full-length human protein was used as the immunogen for the TRP1 antibody.

Klon: TYRR1-1

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 3-6 μg/mL

Immunohistochemistry (FFPE): 3-6 μg/mL for 30 min at RT (1)

Prediluted format: incubate for 30 min at RT (2)

Titering of the TRP1 antibody may be required for optimal performance.

1. Staining of formalin-fixed tissues requires boiling tissue sections in 10  mM Tris with 1  mM EDTA,  pH 9.0, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Andere Bezeichnung: TRP1 (TYRP1 Produkte)

Synonyme: CAS2 antikoerper, CATB antikoerper, GP75 antikoerper, OCA3 antikoerper, TRP antikoerper, TRP1 antikoerper, TYRP antikoerper, b-PROTEIN antikoerper, LOC397853 antikoerper, Trypsin antikoerper, hm:zeh0659 antikoerper, tyrp1 antikoerper, zgc:100893 antikoerper, B antikoerper, TYRP1 antikoerper, tyrp-1 antikoerper, TRP-1 antikoerper, Tyrp antikoerper, b antikoerper, brown antikoerper, isa antikoerper, tyrosinase related protein 1 antikoerper, protease, serine 1 L homeolog antikoerper, tyrosinase-related protein 1b antikoerper, tyrosinase-related protein 1 antikoerper, tyrosinase-related protein 1 L homeolog antikoerper, tyrosinase-related protein 1a antikoerper, TYRP1 antikoerper, prss1.L antikoerper, tyrp1b antikoerper, Tyrp1 antikoerper, tyrp1.L antikoerper, tyrp1 antikoerper, LOC100136490 antikoerper, tyrp-1 antikoerper, tyrp1a antikoerper

Hintergrund: Tyrosinase-Related Protein-1/TYRP1/TRP1 is a melanocyte-specific gene product involved in melanin synthesis. While mouse Tyrp1 possesses dihydroxyindole carboxylic acid oxidase activity, the function in human melanocytes is less clear. In addition to its role in melanin synthesis, Tyrp1 is involved in stabilizing of tyrosinase protein and modulating its catalytic activity. Tyrp1 is also involved in maintenance of melanosome structure and affects melanocyte proliferation and melanocyte cell death. [Wiki]

Gen-ID: 7306

UniProt: P17643