Tyrosinase-Related Protein 1 Antikörper (Middle Region)

Produktnummer ABIN2781815

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Tyrosinase-Related Protein 1 in IHC und WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Ziege, Pferd, Kaninchen, Schaf, Rind (Kuh), Meerschweinchen und Zebrafisch (Danio rerio).Es wurde in 1 Publikation zitiert.

Kurzübersicht für Tyrosinase-Related Protein 1 Antikörper (Middle Region) (ABIN2781815)

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reaktivität: Human, Maus, Ratte, Hund, Ziege, Pferd, Kaninchen, Schaf, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tyrosinase-Related Protein 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails anti-Tyrosinase-Related Protein 1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: TYRP1 Antibody - middle region

Sequenz: NDPIFVLLHT FTDAVFDEWL RRYNADISTF PLENAPIGHN RQYNMVPFWP

Homologie: Cow: 93%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TYRP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TYRP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44315-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Tyrosinase-Related Protein 1 Antikörper (ABIN2781815)

Horibe, Satoh, Shiota, Kumagai, Horike, Takemori, Uesato, Sugie, Obata, Kawahara, Nagaoka: "Induction of melanogenesis by 4'-O-methylated flavonoids in B16F10 melanoma cells." in: Journal of natural medicines, Vol. 67, Issue 4, pp. 705-10, (2013) (PubMed).

Details zu Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Andere Bezeichnung: TYRP1

Hintergrund:

Background Information: TYRP1 catalyses the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. It may regulate or influence the type of melanin synthesized.

Gene Name: Tyrosinase-related protein 1

Alternative Symbols: TRP, CAS2, CATB, GP75, OCA3, TRP1, TYRP, b-PROTEIN

Protein Name: 5,6-dihydroxyindole-2-carboxylic acid oxidase

Molekulargewicht: 61 kDa

Gen-ID: 7306

NCBI Accession: NP_000541

UniProt: P17643