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Tyrosinase-Related Protein 1 Antikörper (AA 257-377)

TYRP1 Reaktivität: Human ELISA, IHC, StM, Coat Wirt: Maus Monoclonal TYRP1-3280 unconjugated
Produktnummer ABIN6940830
  • Target Alle Tyrosinase-Related Protein 1 (TYRP1) Antikörper anzeigen
    Tyrosinase-Related Protein 1 (TYRP1)
    Bindungsspezifität
    • 15
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 257-377
    Reaktivität
    • 104
    • 57
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    Human
    Wirt
    • 79
    • 29
    • 1
    • 1
    Maus
    Klonalität
    • 55
    • 53
    • 2
    Monoklonal
    Konjugat
    • 53
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Tyrosinase-Related Protein 1 Antikörper ist unkonjugiert
    Applikation
    • 65
    • 39
    • 37
    • 30
    • 25
    • 22
    • 14
    • 14
    • 13
    • 5
    • 4
    • 3
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC), Staining Methods (StM), Coating (Coat)
    Spezifität
    It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    A recombinant fragment (around aa 257-377) of human TYRP1 protein (exact sequence is proprietary)
    Klon
    TYRP1-3280
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product TYRP1 Primärantikörper
  • Applikationshinweise

    Positive Control: SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells. Human skin or melanoma tissues (IHC).

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Tyrosinase-Related Protein 1 (TYRP1)
    Andere Bezeichnung
    TYRP1 (TYRP1 Produkte)
    Synonyme
    CAS2 antikoerper, CATB antikoerper, GP75 antikoerper, OCA3 antikoerper, TRP antikoerper, TRP1 antikoerper, TYRP antikoerper, b-PROTEIN antikoerper, LOC397853 antikoerper, Trypsin antikoerper, hm:zeh0659 antikoerper, tyrp1 antikoerper, zgc:100893 antikoerper, B antikoerper, TYRP1 antikoerper, tyrp-1 antikoerper, TRP-1 antikoerper, Tyrp antikoerper, b antikoerper, brown antikoerper, isa antikoerper, tyrosinase related protein 1 antikoerper, protease, serine 1 L homeolog antikoerper, tyrosinase-related protein 1b antikoerper, tyrosinase-related protein 1 antikoerper, tyrosinase-related protein 1 L homeolog antikoerper, tyrosinase-related protein 1a antikoerper, TYRP1 antikoerper, prss1.L antikoerper, tyrp1b antikoerper, Tyrp1 antikoerper, tyrp1.L antikoerper, tyrp1 antikoerper, LOC100136490 antikoerper, tyrp-1 antikoerper, tyrp1a antikoerper
    Molekulargewicht
    75kDa
    Gen-ID
    7306
    UniProt
    P17643
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