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TNFSF15 Antikörper
TNFSF15
Reaktivität: Human
WB, IHC, IF, FACS
Wirt: Maus
Monoclonal
VEGI-1283
unconjugated
Produktnummer ABIN6252818
Produktdetails anti-TNFSF15 Antikörper
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Target
Alle TNFSF15 Antikörper anzeigen
TNFSF15
(Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
Reaktivität
Alle Reaktivitäten für TNFSF15 Antikörper
Human
Wirt
Alle Wirte für TNFSF15 Antikörper
Maus
Klonalität
Alle Klonalitäten für TNFSF15 Antikörper
Monoklonal
Konjugat
Alle Konjugate für TNFSF15 Antikörper
Dieser TNFSF15 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TNFSF15 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
Aufreinigung
Protein G affinity chromatography
Immunogen
A full length human recombinant protein was used as the immunogen for this TL1A antibody.
Klon
VEGI-1283
Isotyp
IgG1 kappa
Top Product
Discover our top product TNFSF15 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Flow Cytometry: 0.5-1 μg/10^6 cells IF: 1-2 μg/mL Western blot: 1-2 μg/mL IHC (FFPE): 1-2 μg/mL Titration of the TL1A antibody may be required for optimal performance.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Details zu TNFSF15
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Target
TNFSF15
(Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
Andere Bezeichnung
VEGI / TL1A (TNFSF15 Produkte )
Synonyme
TTPAL antikoerper, TL1 antikoerper, TL1A antikoerper, VEGI antikoerper, VEGI192A antikoerper, Tl1 antikoerper, Tl1a antikoerper, Vegi antikoerper, tumor necrosis factor superfamily member 15 antikoerper, TNF superfamily member 15 antikoerper, tumor necrosis factor (ligand) superfamily, member 15 antikoerper, TNFSF15 antikoerper, Tnfsf15 antikoerper
Hintergrund
TNF ligand-related molecule 1 is an anti-angiogenic cytokine that is also called Tumor necrosis factor superfamily, member 15 (TNFSF15) and Vascular endothelial growth inhibitor (VEGI/VEGI192A). This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of TL1A has been reported as a marker of poor prognosis in breast cancer.
Gen-ID
9966
UniProt
O95150
Pathways
Positive Regulation of Endopeptidase Activity , Autophagie
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