CD276 Antikörper (Extracellular Domain)
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- Target Alle CD276 Antikörper anzeigen
- CD276
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Bindungsspezifität
- Extracellular Domain
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD276 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Aufreinigung
- B7-H3 Antibody is supplied as protein A purified IgG1.
- Immunogen
- B7-H3 antibody was raised against the extracellular domain of human B7-H3
- Klon
- 4H3
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD276 Primärantikörper
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- Applikationshinweise
- B7-H3 antibody can be used for detection of B7-H3 by Western blot at 0.25 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL and Immunocytochemistry starting at 1 μ,g/mL. For immunofluorescence start at 10 μ,g/mL. Flow cytometry at 1 μ,g/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- B7-H3 Antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- B7-H3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Target
- CD276
- Andere Bezeichnung
- B7-H3 (CD276 Produkte)
- Synonyme
- sc:d0645 antikoerper, zgc:158279 antikoerper, 6030411F23Rik antikoerper, AU016588 antikoerper, B7RP-2 antikoerper, B7h3 antikoerper, B7H3 antikoerper, 4Ig-B7-H3 antikoerper, B7-H3 antikoerper, CD276 molecule antikoerper, CD276 molecule S homeolog antikoerper, CD276 antigen antikoerper, Cd276 molecule antikoerper, CD276 antikoerper, cd276.S antikoerper, cd276 antikoerper, Cd276 antikoerper
- Hintergrund
- CD276, also known as B7-H3, was initially identified as a member of the B7 family of proteins through its homology with previously identified B7 Molecules (1). CD276 mRNA is widely expressed, but its protein expression is usually rather low (2). CD276 has been shown to play a role in both the costimulation as well as the coinhibition of T cell response (3). In a similar fashion, CD276 plays a critical role in the control of antitumor immune responses in some cases, while in others appears to mediate antitumor immunity (4). It thus joins other immune checkpoint proteins as a possible therapeutic target for at least a subset of cancers.
- Molekulargewicht
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Predicted: 57 kDa
Observed: 100 kDa - Gen-ID
- 80381
- NCBI Accession
- NP_001019907
- UniProt
- Q5ZPR3
- Pathways
- Cancer Immune Checkpoints
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