CYLD Antikörper
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- Target Alle CYLD Antikörper anzeigen
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYLD Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Protein A affinity chromatography
- Immunogen
- A recombinant protein fragment from the N-termiinal region of human CYLD was used as the immunogen for this antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product CYLD Primärantikörper
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anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 170-338) antibody
CYLD Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 654-953) antibodyCYLD Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (C-Term) antibodyCYLD Reaktivität: Human, Maus WB, ICC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 204-358) antibodyCYLD Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 5F7F4 unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 269-435), (C-Term) antibodyCYLD Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (pSer418) antibodyCYLD Reaktivität: Human, Maus WB, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 32-45) antibodyCYLD Reaktivität: Human, Maus, Hamster, Huhn, Rind (Kuh), Hund, Meerschweinchen, Pferd, Affe, Kaninchen WB, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 305-582) antibodyCYLD Reaktivität: Human WB, FACS Wirt: Maus Monoclonal 1667CT857-3-6-1 unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) antibodyCYLD Reaktivität: Human, Maus, Ratte ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 854-953) antibodyCYLD Reaktivität: Human ELISA, IF Wirt: Maus Monoclonal 2C3 unconjugated
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- Applikationshinweise
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Western blot: 2-5 μg/mL
Provided assay concentrations are suggestions only, CYLD antibody titration may be required for optimal results. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5 mg/mL
- Buffer
- PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Aliquot and Store at -20C. Avoid freez-thaw cycles.
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- Target
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
- Andere Bezeichnung
- CYLD (CYLD Produkte)
- Synonyme
- BRSS antikoerper, CDMT antikoerper, CYLD1 antikoerper, CYLDI antikoerper, EAC antikoerper, MFT antikoerper, MFT1 antikoerper, SBS antikoerper, TEM antikoerper, USPL2 antikoerper, 2010013M14Rik antikoerper, 2900009M21Rik antikoerper, C130039D01Rik antikoerper, mKIAA0849 antikoerper, cyld antikoerper, LRRGT00003 antikoerper, Rp1 antikoerper, Rp1h antikoerper, CYLD lysine 63 deubiquitinase antikoerper, cylindromatosis (turban tumor syndrome), a antikoerper, CYLD antikoerper, Cyld antikoerper, cylda antikoerper
- Hintergrund
- CYLD is involved in multiple physiological processes including immune response, osteoclastogenesis and spermatogenesis. It is a tumor suppressor via its negative regulation of NF-kB activation. CYLD is a deubiquitinase, removing ubiquitin chains from tumor-necrosis factor receptor-associated factor 2 (TRAF2) and thereby preventing its activation of IkB, a regulator of NF-kB. NF-kB remains sequestered in the cytoplasm, unable to translocate to the nucleus and initiate cell survival and oncogenetic signaling.
- Gen-ID
- 1540
- UniProt
- Q9NQC7
- Pathways
- Apoptose, Activation of Innate immune Response
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