SPPL2B Antikörper (AA 196-229)

Produktnummer ABIN6578288

Produktdetails anti-SPPL2B Antikörper

Target: SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))

Bindungsspezifität: AA 196-229

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPPL2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SPPL2B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 196-229 amino acids from the Central region of human SPPL2B.

Klon: RB53139

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu SPPL2B

Target: SPPL2B (Signal Peptide Peptidase-Like 2B (SPPL2B))

Andere Bezeichnung: SPPL2B (SPPL2B Produkte)

Synonyme: SPPL2B antikoerper, wu:fc16e01 antikoerper, wu:fc85d12 antikoerper, zgc:136525 antikoerper, MGC147524 antikoerper, IMP-4 antikoerper, IMP4 antikoerper, PSH4 antikoerper, PSL1 antikoerper, 3110056O03Rik antikoerper, AW550292 antikoerper, RGD1308556 antikoerper, signal peptide peptidase-like 2 antikoerper, signal peptide peptidase like 2B antikoerper, signal peptide peptidase like 2B S homeolog antikoerper, signal peptide peptidase-like 2B antikoerper, sppl2 antikoerper, sppl2b antikoerper, sppl2b.S antikoerper, SPPL2B antikoerper, Sppl2b antikoerper

Hintergrund: Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF- alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. May play a role in the regulation of innate and adaptive immunity.

Molekulargewicht: 64644

UniProt: Q8TCT7