SEMA7A Antikörper (C-Term)

Produktnummer ABIN6243847

Produktdetails anti-SEMA7A Antikörper

Target: SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))

Bindungsspezifität: AA 521-555, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEMA7A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SEMA7A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 521-555 amino acids from the C-terminal region of human SEMA7A.

Klon: RB30735

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu SEMA7A

Target: SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))

Andere Bezeichnung: SEMA7A (SEMA7A Produkte)

Synonyme: 2900057C09Rik antikoerper, CDw108 antikoerper, H-Sema-L antikoerper, M-Sema-L antikoerper, Semal antikoerper, CD108 antikoerper, H-SEMA-K1 antikoerper, JMH antikoerper, SEMAK1 antikoerper, SEMAL antikoerper, sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A antikoerper, semaphorin 7A (John Milton Hagen blood group) antikoerper, Sema7a antikoerper, SEMA7A antikoerper

Hintergrund: Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.

Molekulargewicht: 74824

UniProt: O75326

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size