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SEMA7A Antikörper (FITC)

SEMA7A Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-150 FITC
Produktnummer ABIN93946
  • Target Alle SEMA7A Antikörper anzeigen
    SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))
    Reaktivität
    • 46
    • 32
    • 24
    • 6
    • 5
    • 1
    • 1
    • 1
    Human
    Wirt
    • 35
    • 12
    • 2
    Maus
    Klonalität
    • 35
    • 14
    Monoklonal
    Konjugat
    • 28
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SEMA7A Antikörper ist konjugiert mit FITC
    Applikation
    • 43
    • 16
    • 13
    • 13
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The antibody MEM-150 reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored extracellular glycoprotein expressed on various cell types including erythrocytes, lymphoblasts, at low levels it is present on circulating lymphocytes.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    HPB-ALL human T cell line
    Klon
    MEM-150
    Isotyp
    IgM
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  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with Fluorescein isothiocyanate (FITC) under optimum conditions. The reagent is free of unconjugated FITC and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    No reconstitution is necessary.
    Buffer
    Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze.
    Avoid prolonged exposure to light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Angelisová, Drbal, Cerný, Hilgert, Horejsí: "Characterization of the human leukocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules." in: Immunobiology, Vol. 200, Issue 2, pp. 234-45, (1999) (PubMed).

    Mudad, Rao, Angelisova, Horejsi, Telen: "Evidence that CDw108 membrane protein bears the JMH blood group antigen." in: Transfusion, Vol. 35, Issue 7, pp. 566-70, (1995) (PubMed).

  • Target
    SEMA7A (Semaphorin 7A, GPI Membrane Anchor (John Milton Hagen Blood Group) (SEMA7A))
    Andere Bezeichnung
    CD108 (SEMA7A Produkte)
    Synonyme
    2900057C09Rik antikoerper, CDw108 antikoerper, H-Sema-L antikoerper, M-Sema-L antikoerper, Semal antikoerper, CD108 antikoerper, H-SEMA-K1 antikoerper, JMH antikoerper, SEMAK1 antikoerper, SEMAL antikoerper, sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A antikoerper, semaphorin 7A (John Milton Hagen blood group) antikoerper, Sema7a antikoerper, SEMA7A antikoerper
    Hintergrund
    Semaphorin 7A (John Milton Hagen blood group),CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors –, plexin C1 and beta1 integrins.,Semaphorin 7a, JMH blood group antigen, SEMAL, SEMAK1
    Gen-ID
    8482
    UniProt
    O75326
    Pathways
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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