Tyrosinase-Related Protein 1 Antikörper

Produktnummer ABIN6191282

Produktdetails anti-Tyrosinase-Related Protein 1 Antikörper

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Tyrosinase-Related Protein 1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Verwendungszweck: Mouse Monoclonal anti-TRP1 (Tyrosinase Related Protein-1) (TA99 + TYRP1/807), Purified, with BSA

Produktmerkmale: This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Aufreinigung: Purified

Immunogen: SK-MEL-23 cells (TA99), Recombinant full-length human TYRP1 protein (TYRP1/807)

Klon: TA99 TYRP1-807

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistology (frozen only) 0.5-1 μg/mL

• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells or Melanoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 200 μg/mL

Buffer: PBS/0.05 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Andere Bezeichnung: TRP1 (TYRP1 Produkte)

Synonyme: CAS2 antikoerper, CATB antikoerper, GP75 antikoerper, OCA3 antikoerper, TRP antikoerper, TRP1 antikoerper, TYRP antikoerper, b-PROTEIN antikoerper, LOC397853 antikoerper, Trypsin antikoerper, hm:zeh0659 antikoerper, tyrp1 antikoerper, zgc:100893 antikoerper, B antikoerper, TYRP1 antikoerper, tyrp-1 antikoerper, TRP-1 antikoerper, Tyrp antikoerper, b antikoerper, brown antikoerper, isa antikoerper, tyrosinase related protein 1 antikoerper, protease, serine 1 L homeolog antikoerper, tyrosinase-related protein 1b antikoerper, tyrosinase-related protein 1 antikoerper, tyrosinase-related protein 1 L homeolog antikoerper, tyrosinase-related protein 1a antikoerper, TYRP1 antikoerper, prss1.L antikoerper, tyrp1b antikoerper, Tyrp1 antikoerper, tyrp1.L antikoerper, tyrp1 antikoerper, LOC100136490 antikoerper, tyrp-1 antikoerper, tyrp1a antikoerper

Molekulargewicht: 75 kDa

Gen-ID: 7306, 270279

UniProt: P17643