GJB1 Antikörper (CF®647)
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- Target Alle GJB1 Antikörper anzeigen
- GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser GJB1 Antikörper ist konjugiert mit CF®647
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Verwendungszweck
- Mouse Monoclonal anti-Connexin-32 (M12.13), CF647 Conjugate
- Produktmerkmale
- This antibody recognizes a protein of 27-32 kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane ?-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities, therefore, one connexin usually cannot fully substitute for another. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Rat junctional complexes
- Klon
- M12-13
- Isotyp
- IgG
- Top Product
- Discover our top product GJB1 Primärantikörper
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- Applikationshinweise
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Immunohistology (frozen) 0.5-1 μg/mL
- Immunofluorescence 1-2 μg/mL Flow cytometry 0.5-1 μg/million cells
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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MCF-7 Cells. Liver, Kidney, Stomach or Tonsil
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))
- Andere Bezeichnung
- Connexin-32 (GJB1 Produkte)
- Synonyme
- GJIC antikoerper, cmtx antikoerper, cmtx1 antikoerper, connexin-30 antikoerper, connexin32 antikoerper, cx30 antikoerper, cx32 antikoerper, gja1 antikoerper, CX32 antikoerper, GJB1 antikoerper, AI118175 antikoerper, Cnx32 antikoerper, Cx32 antikoerper, Gjb-1 antikoerper, CMTX antikoerper, CMTX1 antikoerper, gjb1-a antikoerper, gap junction protein beta 1 antikoerper, connexin 32 antikoerper, probable serine/threonine-protein kinase CST antikoerper, gap junction protein, beta 1 antikoerper, gap junction protein beta 1 L homeolog antikoerper, gjb1 antikoerper, CX32 antikoerper, LOC9303136 antikoerper, GJB1 antikoerper, Gjb1 antikoerper, gjb1.L antikoerper
- Hintergrund
- Charcot Marie Tooth neuropathy X linked, CMTX, CMTX1, Connexin-32, Cx32, GAP junction 28 kDa liver protein, Gap junction beta-1 protein, Gap junction protein beta 1 32kD, GJB1
- Molekulargewicht
- 27-32 kDa
- Gen-ID
- 2705, 333303
- UniProt
- P08034
- Pathways
- Cell-Cell Junction Organization
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