CFTR Antikörper (Biotin)
-
- Target Alle CFTR Antikörper anzeigen
- CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
-
Reaktivität
- Human, Maus
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CFTR Antikörper ist konjugiert mit Biotin
-
Applikation
- Immunofluorescence (IF), Immunohistochemistry (IHC), Immunostaining (ISt), Western Blotting (WB)
- Verwendungszweck
- Mouse Monoclonal anti-CFTR CFTR/1342), Biotin Conjugate
- Produktmerkmale
- This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human full-length CFTR
- Klon
- CFTR-1342
- Isotyp
- IgG2a
- Top Product
- Discover our top product CFTR Primärantikörper
-
-
- Applikationshinweise
-
Immunohistology (formalin) 0.5-1 μg/mL
- Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris, 1 mM EDTA pH 9.0 for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
-
MOLT-4 cells. Pancreas, Kidney or Placenta.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
- Target
- CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
- Andere Bezeichnung
- CFTR (CFTR Produkte)
- Synonyme
- ABC35 antikoerper, ABCC7 antikoerper, CF antikoerper, CFTR/MRP antikoerper, MRP7 antikoerper, TNR-CFTR antikoerper, dJ760C5.1 antikoerper, CFTR antikoerper, AW495489 antikoerper, Abcc7 antikoerper, RGD1561193 antikoerper, abc35 antikoerper, abcc7 antikoerper, cftr/mrp antikoerper, mrp7 antikoerper, tnr-cftr antikoerper, xcftr antikoerper, si:dkey-270i2.2 antikoerper, cystic fibrosis transmembrane conductance regulator antikoerper, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) antikoerper, CFTR antikoerper, cftr-A antikoerper, Cftr antikoerper, cftr antikoerper
- Molekulargewicht
- 165-170 kDa
- Gen-ID
- 1080
-