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CFTR Produkte

(Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte CFTR Kategorien

CFTR Antikörper

High quality antibodies with extensive validation data.

CFTR ELISA Kits

Reliable ELISA kits for a wide range of species.

CFTR Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CFTR Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation FACS, IHC (f)
Validierungen
  • (3)
Kat. Nr. ABIN6939092
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, WB
Validierungen
  • (2)
Kat. Nr. ABIN7180806
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC (f)
Validierungen
  • (2)
Kat. Nr. ABIN7126143
Menge 20 μg
Datenblatt Datenblatt

Empfohlene CFTR ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966205
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962401
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955205
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CFTR Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (3)
Kat. Nr. ABIN3091166
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3133471
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3091165
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CFTR Produkten

Ye, Onodera, Blanchard, Kusminski, Esser, Brekken, Scherer: "β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis." in: The American journal of pathology, Vol. 189, Issue 4, pp. 813-825, (2019) (PubMed).

Romani, Oikonomou, Moretti, Iannitti, DAdamo, Villella, Pariano, Sforna, Borghi, Bellet, Fallarino, Pallotta, Servillo, Ferrari, Puccetti, Kroemer, Pessia, Maiuri, Goldstein, Garaci: "Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis." in: Nature medicine, Vol. 23, Issue 5, pp. 590-600, (2017) (PubMed).

Xu, Yong, Li, Dong, Yu, Fu, Hu: "High level of CFTR expression is associated with tumor aggression and knockdown of CFTR suppresses proliferation of ovarian cancer in vitro and in vivo." in: Oncology reports, Vol. 33, Issue 5, pp. 2227-34, (2015) (PubMed).

Rottner, Kunzelmann, Mergey, Freyssinet, Martínez: "Exaggerated apoptosis and NF-kappaB activation in pancreatic and tracheal cystic fibrosis cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 11, pp. 2939-48, (2007) (PubMed).

Di, Brown, Deriy, Li, Szeto, Chen, Huang, Tong, Naren, Bindokas, Palfrey, Nelson: "CFTR regulates phagosome acidification in macrophages and alters bactericidal activity." in: Nature cell biology, Vol. 8, Issue 9, pp. 933-44, (2006) (PubMed).

Benlloch, Ortega, Ferrer, Segarra, Obrador, Asensi, Carretero, Estrela: "Acceleration of glutathione efflux and inhibition of gamma-glutamyltranspeptidase sensitize metastatic B16 melanoma cells to endothelium-induced cytotoxicity." in: The Journal of biological chemistry, Vol. 280, Issue 8, pp. 6950-9, (2005) (PubMed).

Kulka, Dery, Nahirney, Duszyk, Befus: "Differential regulation of cystic fibrosis transmembrane conductance regulator by interferon gamma in mast cells and epithelial cells." in: The Journal of pharmacology and experimental therapeutics, Vol. 315, Issue 2, pp. 563-70, (2005) (PubMed).

Laverty, McWilliams, Sheldon, Arnason: "PTH stimulates a Cl(-)-dependent and EIPA-sensitive current in chick proximal tubule cells in culture." in: American journal of physiology. Renal physiology, Vol. 284, Issue 5, pp. F987-95, (2003) (PubMed).

Dalby-Payne, OLoughlin, Gunning: "Polarization of specific tropomyosin isoforms in gastrointestinal epithelial cells and their impact on CFTR at the apical surface." in: Molecular biology of the cell, Vol. 14, Issue 11, pp. 4365-75, (2003) (PubMed).

Kulka, Gilchrist, Duszyk, Befus: "Expression and functional characterization of CFTR in mast cells." in: Journal of leukocyte biology, Vol. 71, Issue 1, pp. 54-64, (2002) (PubMed).

Synonyme und alternative Namen zu CFTR

cystic fibrosis transmembrane conductance regulator (CFTR), cystic fibrosis transmembrane conductance regulator (cftr-A), cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (CFTR), cystic fibrosis transmembrane conductance regulator (Cftr), cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (cftr), ABC35, abc35, ABCC7, Abcc7, abcc7, AW495489, CF, CFTR, CFTR/MRP, cftr/mrp, dJ760C5.1, MRP7, mrp7, RGD1561193, si:dkey-270i2.2, TNR-CFTR, tnr-cftr, xcftr

Bezeichner auf Proteinebene für CFTR

  • cAMP-dependent chloride channel
  • channel conductance-controlling ATPase
  • cystic fibrosis transmembrane conductance regulator
  • cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
  • cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)
  • ATP-binding cassette sub-family C member 7
  • ATP-binding cassette transporter sub-family C member 7
  • ATP-binding cassette, subfamily c, member 7
  • cystic fibrosis transmembrane conductance regulator homolog
  • cystic fibrosis transmembrane conductance regulator homolog; ATP-binding cassette, subfamily c, member 7
  • CFTR chloride channel
  • chloride channel
  • CFTR cAMP-dependent chloride channel protein
  • Channel conductance-controlling ATPase
  • abcc7
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