CFTR Antikörper (AA 1161-1480)

Produktnummer ABIN6138469

Produktdetails anti-CFTR Antikörper

Target: CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))

Bindungsspezifität: AA 1161-1480

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CFTR Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Western Blotting (WB)

Sequenz: SRVFKFIDMP TEGKPTKSTK PYKNGQLSKV MIIENSHVKK DDIWPSGGQM TVKDLTAKYT EGGNAILENI SFSISPGQRV GLLGRTGSGK STLLSAFLRL LNTEGEIQID GVSWDSITLQ QWRKAFGVIP QKVFIFSGTF RKNLDPYEQW SDQEIWKVAD EVGLRSVIEQ FPGKLDFVLV DGGCVLSHGH KQLMCLARSV LSKAKILLLD EPSAHLDPVT YQIIRRTLKQ AFADCTVILC EHRIEAMLEC QQFLVIEENK VRQYDSIQKL LNERSLFRQA ISPSDRVKLF PHRNSSKCKS KPQIAALKEE TEEEVQDTRL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1161-1480 of human CFTR (NP_000483.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CFTR

Target: CFTR (Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR))

Andere Bezeichnung: CFTR (CFTR Produkte)

Synonyme: ABC35 antikoerper, ABCC7 antikoerper, CF antikoerper, CFTR/MRP antikoerper, MRP7 antikoerper, TNR-CFTR antikoerper, dJ760C5.1 antikoerper, CFTR antikoerper, AW495489 antikoerper, Abcc7 antikoerper, RGD1561193 antikoerper, abc35 antikoerper, abcc7 antikoerper, cftr/mrp antikoerper, mrp7 antikoerper, tnr-cftr antikoerper, xcftr antikoerper, si:dkey-270i2.2 antikoerper, cystic fibrosis transmembrane conductance regulator antikoerper, cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) antikoerper, CFTR antikoerper, cftr-A antikoerper, Cftr antikoerper, cftr antikoerper

Hintergrund: This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene.,CFTR,ABC35,ABCC7,CF,CFTR/MRP,MRP7,TNR-CFTR,dJ760C5.1,Cancer,Cell Biology & Developmental Biology,Endocrine & Metabolism,CFTR

Molekulargewicht: 69 kDa/161 kDa/168 kDa

Gen-ID: 1080

UniProt: P13569