IFNA2 Antikörper (CF®568)

Produktnummer ABIN6170893

Produktdetails anti-IFNA2 Antikörper (CF®568)

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNA2 Antikörper ist konjugiert mit CF®568

Applikation: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat), Blocking Peptide (BP), Activity Assay (AcA)

Verwendungszweck: Mouse Monoclonal anti-Interferon alpha-2 (N27), CF568 Conjugate

Produktmerkmale: This antibody recognizes a protein of 16-27 kDa, identified as human interferon-i±II (IFN-i±II). Its epitope maps between aa43-53 of the IFN-i±II) (total aa172). This MAb is specific for IFN-i±(II) and does not cross-react with IFN-i±(I). Epitopes of N27 and N39 MAb s are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-i±(II) after viral infections. The IFN-i± family consists of 24 or more genes or pseudo-genes. IFN-i±II) is one of the two distinct families (I and II) of human IFN-i±. The i± interferons are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Purified recombinant human IFN-alpha2

Klon: N27

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry 0.5-1 μg/million cells in 0.1 mL

• Blocking activity order Ab without azide
• Immunofluorescence 0.5-1 μg/mL
• ELISA For coating, order Ab without BSA
• Optimal dilution for a specific application should be determined by user

Kommentare:

Stimulated human peripheral blood mononuclear cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu IFNA2

Target: IFNA2 (Interferon, alpha 2 (IFNA2))

Andere Bezeichnung: Interferon alpha-2 (IFNA2 Produkte)

Synonyme: IFN-alphaA antikoerper, IFNA antikoerper, IFNA2B antikoerper, INFA2 antikoerper, Ifa2 antikoerper, IFNA2 antikoerper, interferon alpha 2 antikoerper, interferon, alpha 2 antikoerper, interferon-alpha-2 antikoerper, interferon alpha-2 antikoerper, IFNA2 antikoerper, Ifna2 antikoerper, ifna2 antikoerper, IFN-ALPHA2 antikoerper, LOC102142148 antikoerper

Hintergrund: Alpha 2a interferon, IFN alpha, IFN-alpha-2, IFNA, IFNA2, IFNA2B, Interferon alpha 2a, Interferon alpha 2b, Interferon alpha-2, Interferon alpha-A, LeIF2, LeIFA

Molekulargewicht: 16-27 kDa

Gen-ID: 3440

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C