VEGFA Antikörper
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- Target Alle VEGFA Antikörper anzeigen
- VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
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Reaktivität
- Human, Ratte, Maus, Hund, Kaninchen
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser VEGFA Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Verwendungszweck
- Mouse Monoclonal anti-VEGF-A (VEGF/1063), Purified, BSA-free
- Produktmerkmale
- This MAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Aufreinigung
- Purified
- Immunogen
- Human VEGF189 recombinant protein
- Klon
- VEGF-1063
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product VEGFA Primärantikörper
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- Applikationshinweise
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Immunohistology formalin-fixed 2-4 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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Tumor cells in astrocytomas, breast or ovarian carcinomas.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS (no BSA, no azide)
- Konservierungsmittel
- Azide free
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- Target
- VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
- Andere Bezeichnung
- VEGF-A (VEGFA Produkte)
- Synonyme
- MVCD1 antikoerper, VEGF antikoerper, VPF antikoerper, Vegf antikoerper, Vegf120 antikoerper, Vegf164 antikoerper, Vegf188 antikoerper, Vpf antikoerper, vegf antikoerper, vegfa antikoerper, wu:fj82c06 antikoerper, VEGF-A antikoerper, VEGF164 antikoerper, eVEGF120 antikoerper, eVEGF164 antikoerper, vegf-a antikoerper, vpf antikoerper, vefg antikoerper, si:dkey-14d8.3 antikoerper, wu:fd42e02 antikoerper, vascular endothelial growth factor A antikoerper, vascular endothelial growth factor Aa antikoerper, vascular endothelial growth factor A L homeolog antikoerper, vascular endothelial growth factor Ab antikoerper, VEGFA antikoerper, Vegfa antikoerper, vegfaa antikoerper, vegfa.L antikoerper, vegfa antikoerper, vegfab antikoerper
- Hintergrund
- MVCD1, Vascular Endothelial Growth Factor A (VEGF-A), Vascular Permeability Factor (VPF), VEGFA
- Molekulargewicht
- 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing)
- Gen-ID
- 7422, 73793
- UniProt
- P15692
- Pathways
- RTK Signalweg, Glycosaminoglycan Metabolic Process, Regulation of Cell Size, Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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